ISSN: 1305-385X
Hakkında: Özel sayılar şeklinde yayınlanır.
|
|
|
Adjunctive Therapies In St-elevation Myocardial Infarction
Dr. Aytül BELGİa
aKardiyoloji AD, Akdeniz Üniversitesi Tıp Fakültesi, ANTALYA
Primary percutaneous intervention (PCI) is an effective reperfusion strategy for acute MI patients, which has evolved significantly in the last decade. Catheter-based treatment depends on a number of factors. Therefore, globally, pharmacological therapy remains the primary means of achieving reperfusion in ST-elevation myocardial infarction (STEMI). While many adjunctive therapies have contributed to its success, substantial obstacles remain before optimal reperfusion can be achieved. Anti-platelet therapy with aspirin, clopidogrel and GP IIb/IIIa inhibitors reduces early ischemic complications, improves microvascular function and, potentially, affects the inflammatory response to ischemic injury. Antithrombotic therapy as an adjunct to thrombolysis improves the speed and extent of artery recanalization and reduces the incidence of secondary ischemic complications. This article reviews adjunctive therapies and evaluates the evidence for their use in patients with STEMI.Keywords: ST-elevation myocardial infarction, adjunctive therapyTurkiye Klinikleri J Int Med Sci 2006, 2(42):29-33
|
|
|
|
|
