ISSN: 1305-385X
Hakkında: Özel sayılar şeklinde yayınlanır.
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Cardio- Vascular Adaptations To Pregnancy
Dr. Gültaç ÖZBAYa
aKardiyoloji AD, Trakya Üniversitesi Tıp Fakültesi, EDİRNE
Pregnancy causes dramatic and usually reversible changes in mother’s cardio-vascular system. Many adaptations in cardiac and vascular function during pregnancy that protect the mother from stress include changes in blood pressure, sudden decreases in venous return to the heart, blood loss and the higher oxygen and workload demands of pregnancy, labor. Many hormonal changes such as renin- angiotensin-aldosteron system, atrial natriuretic peptides, progestins,endotelins ve prostaglandines play important role in adaptations. While plasma volume, red blood cell mass, cardiac output, heart rate increase, on the contrary these, periferic vascular resistance and arterial pressures decrease. Whereras, pulmonary capillary pressure (pulmonary wedge pressure) unchanges. During pregnancy, elevation of the diaphragm causes a increse in cardiac borders. The architecture of the heart is remodeled such that end diastolic volume is increased without an increase end diastolic pressure. Ventricular wall muscle mass and end-diastolic volume increase in 2nd and 3rd trimester without in associated increase in systolic volume. As compliance increases without a concomittant reduction in ejection fraction as a result, myocardial contractility increases slightly. Cardiac output, O2 comsuption, heart rate and arterial pressures increase excessively during labor and delivery.Keywords: Pregnancy, hemodynamic changes, cardiac output, systemic vascular resistance, arterial pressureTurkiye Klinikleri J Int Med Sci 2005, 1(50):1-5
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